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致使

使 zhì shǐ to cause / to result in
zhì (bound form) fine; delicate; exquisite
zhì (literary) to send; to transmit; to convey / (bound form) to cause; to lead to; consequently
 使 shǐ to make / to cause / to enable / to use / to employ / to send / to instruct sb to do sth / envoy / messenger
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